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Talk:Androgen

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There seems to be no mention of intracellular T synthesis, is this intentional?

[edit]

As can be seen in sources such as here and here, a certainly not insignificant amount of female testosterone seems to be made by intake of DHEA-S, which then goes through STS and a few other enzymes to become T and DHT before being metabolised and conjugated into inactive glucuronide forms and released. The article at present mostly seems to suggest that circulating androgen levels are metabolised in either the adrenals or gonads, and misses the bigger picture that many tissues in the body can and do metabolise their own sources of more active androgens.

Quilavan (talk) 20:40, 4 July 2021 (UTC)[reply]